A driver has died after a three-vehicle road crash near Dunblane.
Police said a Honda Civic, a Mercedes Sprinter and a Volvo articulated lorry were involved in the incident at the Keir roundabout on the A9 at about 6.25pm on Thursday.
A 25-year-old man in the Honda died as a result of the collision, officers said.
A 26-year-old female passenger in the Honda was seriously injured and remains in hospital while the 41-year-old driver of the Mercedes is also in hospital.
The A9 was closed in both directions for several hours and reopened at about midnight.
Sergeant Michael Montague, of Forth Valley road policing unit, said: "A man has died in this collision and a passenger and one other driver seriously injured, and we are keen to hear from anyone who witnessed the collision.
"Anyone with information that can assist us with our ongoing inquiries is asked to contact officers via 101."
Meanwhile, a 21-year-old man has died following a road crash in the Lambhill area of Glasgow on Thursday.
The incident occurred at about 5.20pm when a Honda CB600 motorbike was involved in a collision with a Renault Clio and a Metrocab on Balmore Road near to its junction with Skirsa Street.
The motorcyclist was seriously injured at the scene and taken to Glasgow Royal Infirmary, where he later died.
Both drivers of the Renault Clio and the Metrocab were uninjured.
Constable Adnan Alam, of the divisional road policing unit at Helen Street, said: "I am keen to speak to anyone who witnessed the crash or may have seen the motorcyclist driving in the area before the crash took place.
"Anyone with information should contact officers at the road policing complex at Helen Street through 101."
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